GPU comparison

MI250X vs Quadro P5000

Specifications and current cloud pricing, side by side.

CDNA 2vsPascalUpdated 30 days ago

The MI250X wins for the most common use case of large model training because its 128 GB VRAM, 3277 GB/s bandwidth, and 383 TFLOPS dense FP16 exceed the Quadro P5000 specifications by wide margins.

MI250X listed from $1.28/GPU/hrQuadro P5000 listed from $0.78/GPU/hr

Right now, from live stock

  • Cheapest right now: Quadro P5000 at $0.78/hr on Paperspace

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  • Most providers in stock: Quadro P5000 (1)

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Specifications Compared

SpecMI250XQuadro P5000
TDP560W180W
VRAM128 GB16 GB
CUDA CoresNot published2,560
Memory TypeHBM2eGDDR5X
ArchitectureCDNA 2Pascal
FP16 (dense)383 TFLOPSNot published
Form FactorsOAMPCIe
INT8 (dense)383 TOPSNot published
InterconnectInfinity Fabric, PCIe 4.0PCIe 3.0
FP32 Performance47.9 TFLOPS8.9 TFLOPS
FP64 Performance47.9 TFLOPSNot published
Memory Bandwidth3,277 GB/s288 GB/s

Performance Analysis

The MI250X delivers FP16 dense performance at 383 TFLOPS while the Quadro P5000 provides no published FP16 figure. FP32 performance reaches 47.9 TFLOPS dense on the MI250X against 8.9 TFLOPS on the Quadro P5000. This FP16 dense to FP32 ratio on the MI250X equals 383 TFLOPS dense divided by 47.9 TFLOPS. The higher memory bandwidth of 3277 GB/s on the MI250X supports larger batch sizes during training and inference compared with 288 GB/s on the Quadro P5000. INT8 dense performance on the MI250X measures 383 TOPS. These differences translate to greater capacity for parallel tensor operations on the MI250X in workloads that fit within its 128 GB VRAM.

Current On-Demand Offers

Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.

MI250X

MI250X is not offered on-demand by any provider we track right now. See the MI250X rental page for last-seen listed prices and a price alert.

Quadro P5000

ProviderRegionGPUsPer GPU / hrInstance / hrDeploy
Paperspaceca12$0.78$1.56Deploy

1 provider in stock, 6 offers (cheapest per provider shown). All Quadro P5000 offers, price history and alerts

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When to Choose the MI250X

The MI250X suits scenarios that require 128 GB HBM2e VRAM and 3277 GB/s memory bandwidth. Workloads that utilize 383 TFLOPS dense FP16 or 47.9 TFLOPS FP32 benefit from its specifications over the Quadro P5000. Infinity Fabric interconnect further supports multi GPU scaling in large scale deployments.

When to Choose the Quadro P5000

The Quadro P5000 fits environments limited to 180W TDP and PCIe form factor constraints. Systems that operate under PCIe 3.0 interconnect and require only 8.9 TFLOPS FP32 align with its specifications. Lower power draw makes it appropriate for compact or legacy server setups.

Use Cases

LLM Training
MI250X

The MI250X provides 128 GB VRAM and 383 TFLOPS dense FP16 that enable training of larger models than the Quadro P5000 can support.

LLM Inference
MI250X

The MI250X 3277 GB/s bandwidth and 383 TOPS dense INT8 allow higher throughput for inference batches compared with the Quadro P5000.

Fine-tuning
MI250X

The MI250X 47.9 TFLOPS FP32 and 128 GB VRAM accommodate fine tuning workloads that exceed the 16 GB limit of the Quadro P5000.

Stable Diffusion
Quadro P5000

The Quadro P5000 180W TDP and PCIe form factor suit lighter inference tasks within its 8.9 TFLOPS FP32 capability.

Scientific Computing
MI250X

The MI250X 47.9 TFLOPS FP32 and high bandwidth support compute intensive scientific simulations beyond the Quadro P5000 specifications.

Frequently Asked Questions

How does memory bandwidth compare on these GPUs?▾

Memory bandwidth measures 3277 GB/s on the MI250X. It measures 288 GB/s on the Quadro P5000.

What FP32 performance do the GPUs deliver?▾

FP32 performance reaches 47.9 TFLOPS on the MI250X. It reaches 8.9 TFLOPS on the Quadro P5000.

Which GPU has higher power consumption?▾

The MI250X TDP is 560W. The Quadro P5000 TDP is 180W.

What architectures do these GPUs use?▾

The MI250X uses CDNA 2 architecture. The Quadro P5000 uses Pascal architecture.

Which is cheaper to rent, the MI250X or the Quadro P5000?▾

Cloud rental prices for both the MI250X and Quadro P5000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI250X have compared to the Quadro P5000?▾

The MI250X has 128 GB of HBM2e memory. The Quadro P5000 has 16 GB of GDDR5X memory.

Can I find MI250X and Quadro P5000 GPUs available to rent right now?▾

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI250X and the Quadro P5000?▾

The MI250X uses the CDNA 2 architecture (2021) while the Quadro P5000 uses Pascal (2016). The MI250X has 128 GB of HBM2e at 3,277 GB/s; the Quadro P5000 has 16 GB of GDDR5X at 288 GB/s, so the MI250X has 11.4x the memory bandwidth of the Quadro P5000.

Rent these GPUs

Each GPU page lists every current on-demand offer by provider, per GPU-hour, updated every minute.

Related comparisons

How this page is made

  • Specifications come from the NVIDIA, AMD and Intel datasheets for the MI250X and the Quadro P5000. Dense and sparse throughput are listed separately.
  • Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
  • The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
  • Read how we collect the data, or report an error on this page.

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