Specifications Compared
| Spec | MI250X | Quadro P6000 |
|---|---|---|
| TDP | 560W | 250W |
| VRAM | 128 GB | 24 GB |
| CUDA Cores | Not published | 3,840 |
| Memory Type | HBM2e | GDDR5X |
| Architecture | CDNA 2 | Pascal |
| FP16 (dense) | 383 TFLOPS | Not published |
| Form Factors | OAM | PCIe |
| INT8 (dense) | 383 TOPS | Not published |
| Interconnect | Infinity Fabric, PCIe 4.0 | PCIe 3.0 |
| FP32 Performance | 47.9 TFLOPS | 12.6 TFLOPS |
| FP64 Performance | 47.9 TFLOPS | Not published |
| Memory Bandwidth | 3,277 GB/s | 432 GB/s |
Performance Analysis
The MI250X delivers 383 TFLOPS dense FP16 against an FP16 figure not published by the vendor for the Quadro P6000. In FP32 the MI250X supplies 47.9 TFLOPS while the Quadro P6000 supplies 12.6 TFLOPS yielding a ratio of 3.8 times. This FP32 ratio indicates the MI250X can complete the same dense computation in roughly one quarter the time when both GPUs run at full FP32 utilization. Memory bandwidth of 3277 GB/s on the MI250X versus 432 GB/s on the Quadro P6000 allows the MI250X to sustain larger batch sizes during training or inference before memory becomes the limiting factor. The 128 GB capacity on the MI250X further supports these larger batches compared with the 24 GB capacity on the Quadro P6000.
Current On-Demand Offers
Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.
MI250X
MI250X is not offered on-demand by any provider we track right now. See the MI250X rental page for last-seen listed prices and a price alert.
Quadro P6000
| Provider | Region | GPUs | Per GPU / hr | Instance / hr | Deploy |
|---|---|---|---|---|---|
| Paperspace | ams1 | 1 | $1.10 | — | Deploy |
1 provider in stock, 6 offers (cheapest per provider shown). All Quadro P6000 offers, price history and alerts
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When to Choose the MI250X
The MI250X suits LLM training and scientific computing tasks that require 128 GB HBM2e memory and 3277 GB/s bandwidth. Its 383 TFLOPS dense FP16 rating supports accelerated dense matrix operations in these workloads.
When to Choose the Quadro P6000
The Quadro P6000 fits inference or fine tuning jobs where 250W TDP and PCIe form factor align with existing 2016 era servers. Its 24 GB GDDR5X memory meets requirements for smaller models that do not exceed this capacity.
Use Cases
The MI250X supplies 128 GB memory and 383 TFLOPS dense FP16 that exceed the Quadro P6000 specifications.
The MI250X 3277 GB/s bandwidth supports larger concurrent inference batches than the 432 GB/s on the Quadro P6000.
The MI250X 47.9 TFLOPS FP32 rating completes fine tuning steps faster than the 12.6 TFLOPS FP32 on the Quadro P6000.
Both GPUs can run the workload yet the MI250X handles larger batches while the Quadro P6000 fits lower power setups.
The MI250X 128 GB capacity and Infinity Fabric interconnect suit large scale scientific simulations better than the Quadro P6000.
Frequently Asked Questions
What is the memory bandwidth of each GPU?▾
The MI250X reaches 3277 GB/s and the Quadro P6000 reaches 432 GB/s.
Which GPU offers higher FP32 performance?▾
The MI250X delivers 47.9 TFLOPS FP32 while the Quadro P6000 delivers 12.6 TFLOPS FP32.
What TDP values do the GPUs carry?▾
The MI250X carries a TDP of 560W and the Quadro P6000 carries a TDP of 250W.
Which interconnect does each GPU use?▾
The MI250X uses Infinity Fabric and PCIe 4.0 while the Quadro P6000 uses PCIe 3.0.
When was each architecture released?▾
The MI250X uses CDNA 2 architecture released in 2021 and the Quadro P6000 uses Pascal architecture released in 2016.
Which is cheaper to rent, the MI250X or the Quadro P6000?▾
Cloud rental prices for both the MI250X and Quadro P6000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.
How much VRAM does the MI250X have compared to the Quadro P6000?▾
The MI250X has 128 GB of HBM2e memory. The Quadro P6000 has 24 GB of GDDR5X memory.
Can I find MI250X and Quadro P6000 GPUs available to rent right now?▾
Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.
What is the main difference between the MI250X and the Quadro P6000?▾
The MI250X uses the CDNA 2 architecture (2021) while the Quadro P6000 uses Pascal (2016). The MI250X has 128 GB of HBM2e at 3,277 GB/s; the Quadro P6000 has 24 GB of GDDR5X at 432 GB/s, so the MI250X has 7.6x the memory bandwidth of the Quadro P6000.
Rent these GPUs
Each GPU page lists every current on-demand offer by provider, per GPU-hour, updated every minute.
Related comparisons
How this page is made
- Specifications come from the NVIDIA, AMD and Intel datasheets for the MI250X and the Quadro P6000. Dense and sparse throughput are listed separately.
- Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
- The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
- Read how we collect the data, or report an error on this page.
Next steps
- Rent MI250XEvery current offer by provider, daily price history and a price alert.
- Rent QUADRO P6000Every current offer by provider, daily price history and a price alert.
- GPU price indexHow on-demand prices for the major GPUs have moved, updated daily.
- All GPUsEvery GPU we track, with current lows and provider counts.