Specifications Compared
| Spec | MI250X | Quadro RTX 4000 |
|---|---|---|
| TDP | 560W | 125W |
| VRAM | 128 GB | 8 GB |
| CUDA Cores | Not published | 2,304 |
| Memory Type | HBM2e | GDDR6 |
| Architecture | CDNA 2 | Turing |
| FP16 (dense) | 383 TFLOPS | 57 TFLOPS |
| Form Factors | OAM | PCIe |
| INT8 (dense) | 383 TOPS | Not published |
| Interconnect | Infinity Fabric, PCIe 4.0 | PCIe 3.0 |
| Tensor Cores | Not published | 288 |
| FP32 Performance | 47.9 TFLOPS | 7.1 TFLOPS |
| FP64 Performance | 47.9 TFLOPS | Not published |
| Memory Bandwidth | 3,277 GB/s | 416 GB/s |
Performance Analysis
The MI250X dense FP16 rating of 383 TFLOPS exceeds the Quadro RTX 4000 dense FP16 rating of 57 TFLOPS by a factor of 6.7. This gap indicates that training workloads using dense FP16 arithmetic complete iterations faster on the MI250X than on the Quadro RTX 4000. The MI250X FP32 rating of 47.9 TFLOPS likewise exceeds the Quadro RTX 4000 FP32 rating of 7.1 TFLOPS by a factor of 6.7 so inference tasks using FP32 arithmetic also finish sooner on the MI250X. Memory bandwidth of 3277 GB per second on the MI250X versus 416 GB per second on the Quadro RTX 4000 allows the MI250X to sustain larger batch sizes before memory capacity of 128 GB versus 8 GB becomes the limiting factor.
Current On-Demand Offers
Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.
MI250X
MI250X is not offered on-demand by any provider we track right now. See the MI250X rental page for last-seen listed prices and a price alert.
Quadro RTX 4000
| Provider | Region | GPUs | Per GPU / hr | Instance / hr | Deploy |
|---|---|---|---|---|---|
| Paperspace | ny2 | 2 | $0.56 | $1.12 | Deploy |
1 provider in stock, 5 offers (cheapest per provider shown). All Quadro RTX 4000 offers, price history and alerts
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When to Choose the MI250X
The MI250X suits workloads that require the 128 GB HBM2e capacity and the 3277 GB per second bandwidth together with 383 TFLOPS dense FP16. Scientific computing jobs that fit within the 560 W TDP envelope benefit from the 47.9 TFLOPS FP32 rating and the Infinity Fabric interconnect.
When to Choose the Quadro RTX 4000
The Quadro RTX 4000 suits workloads that remain within the 8 GB GDDR6 capacity and that operate under the 125 W TDP limit. Inference tasks that need only 57 TFLOPS dense FP16 and 7.1 TFLOPS FP32 fit the PCIe form factor and PCIe 3.0 interconnect of this GPU.
Use Cases
The MI250X supplies 383 TFLOPS dense FP16 and 128 GB memory while the Quadro RTX 4000 supplies 57 TFLOPS dense FP16 and 8 GB memory.
The MI250X supplies 47.9 TFLOPS FP32 and 3277 GB per second bandwidth while the Quadro RTX 4000 supplies 7.1 TFLOPS FP32 and 416 GB per second bandwidth.
The MI250X supplies 383 TOPS dense INT8 and 128 GB memory while the Quadro RTX 4000 supplies 8 GB memory.
The Quadro RTX 4000 operates at 125 W TDP and fits PCIe slots while the MI250X requires 560 W TDP and OAM form factor.
The MI250X supplies 47.9 TFLOPS FP32 and Infinity Fabric interconnect while the Quadro RTX 4000 supplies PCIe 3.0 interconnect.
Frequently Asked Questions
What are the FP16 ratings for each GPU?▾
The MI250X lists 383 TFLOPS dense FP16. The Quadro RTX 4000 lists 57 TFLOPS dense FP16.
What are the FP32 ratings for each GPU?▾
The MI250X lists 47.9 TFLOPS FP32. The Quadro RTX 4000 lists 7.1 TFLOPS FP32.
What TDP values do the GPUs carry?▾
The MI250X carries a 560 W TDP. The Quadro RTX 4000 carries a 125 W TDP.
Which interconnect does each GPU use?▾
The MI250X uses Infinity Fabric and PCIe 4.0. The Quadro RTX 4000 uses PCIe 3.0.
Which architecture does each GPU use?▾
The MI250X uses CDNA 2 architecture. The Quadro RTX 4000 uses Turing architecture.
Which is cheaper to rent, the MI250X or the Quadro RTX 4000?▾
Cloud rental prices for both the MI250X and Quadro RTX 4000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.
How much VRAM does the MI250X have compared to the Quadro RTX 4000?▾
The MI250X has 128 GB of HBM2e memory. The Quadro RTX 4000 has 8 GB of GDDR6 memory.
Can I find MI250X and Quadro RTX 4000 GPUs available to rent right now?▾
Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.
What is the main difference between the MI250X and the Quadro RTX 4000?▾
The MI250X uses the CDNA 2 architecture (2021) while the Quadro RTX 4000 uses Turing (2018). The MI250X delivers 6.7x the dense FP16 throughput (383 vs 57 TFLOPS, both without sparsity) and 7.9x the memory bandwidth of the Quadro RTX 4000.
Rent these GPUs
Each GPU page lists every current on-demand offer by provider, per GPU-hour, updated every minute.
Related comparisons
How this page is made
- Specifications come from the NVIDIA, AMD and Intel datasheets for the MI250X and the Quadro RTX 4000. Dense and sparse throughput are listed separately.
- Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
- The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
- Read how we collect the data, or report an error on this page.
Next steps
- Rent MI250XEvery current offer by provider, daily price history and a price alert.
- Rent QUADRO RTX 4000Every current offer by provider, daily price history and a price alert.
- GPU price indexHow on-demand prices for the major GPUs have moved, updated daily.
- All GPUsEvery GPU we track, with current lows and provider counts.