GPU comparison

MI250X vs Quadro RTX 5000

Specifications and current cloud pricing, side by side.

CDNA 2vsTuringUpdated 34 days ago

The MI250X wins for the most common use case of LLM training because its 383 TFLOPS dense FP16 and 128 GB memory exceed the 89.2 TFLOPS dense FP16 and 16 GB memory of the Quadro RTX 5000 by wide margins.

MI250X listed from $1.28/GPU/hrQuadro RTX 5000 listed from $0.82/GPU/hr

Right now, from live stock

  • Cheapest right now: Quadro RTX 5000 at $0.82/hr on Paperspace

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  • Most providers in stock: Quadro RTX 5000 (1)

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Specifications Compared

SpecMI250XQuadro RTX 5000
TDP560W230W
VRAM128 GB16 GB
CUDA CoresNot published3,072
Memory TypeHBM2eGDDR6
ArchitectureCDNA 2Turing
FP16 (dense)383 TFLOPS89.2 TFLOPS
Form FactorsOAMPCIe
INT8 (dense)383 TOPS178.4 TOPS
InterconnectInfinity Fabric, PCIe 4.0NVLink, PCIe 3.0
Tensor CoresNot published384
FP32 Performance47.9 TFLOPS11.2 TFLOPS
FP64 Performance47.9 TFLOPSNot published
Memory Bandwidth3,277 GB/s448 GB/s

Performance Analysis

Dense FP16 performance reaches 383 TFLOPS on the MI250X compared with 89.2 TFLOPS dense FP16 on the Quadro RTX 5000 which implies substantially larger batch sizes during training or inference when memory capacity of 128 GB is available. The FP32 figures of 47.9 TFLOPS on the MI250X versus 11.2 TFLOPS on the Quadro RTX 5000 indicate similar scaling for precision sensitive workloads. Memory bandwidth of 3277 GB/s versus 448 GB/s directly limits data movement rates and therefore constrains achievable throughput on the lower bandwidth device. Dense INT8 ratings of 383 TOPS versus 178.4 TOPS follow the same pattern and favor the MI250X for quantized inference tasks. Higher TDP of 560W on the MI250X must be weighed against these compute and bandwidth advantages.

Current On-Demand Offers

Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.

MI250X

MI250X is not offered on-demand by any provider we track right now. See the MI250X rental page for last-seen listed prices and a price alert.

Quadro RTX 5000

ProviderRegionGPUsPer GPU / hrInstance / hrDeploy
Paperspaceny21$0.82—Deploy

1 provider in stock, 2 offers (cheapest per provider shown). All Quadro RTX 5000 offers, price history and alerts

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When to Choose the MI250X

The MI250X suits workloads that require 128 GB HBM2e memory and 383 TFLOPS dense FP16 to accommodate large models. Its 3277 GB/s bandwidth and Infinity Fabric interconnect support distributed training scenarios where the 560W TDP is acceptable.

When to Choose the Quadro RTX 5000

The Quadro RTX 5000 fits environments constrained to 230W TDP and PCIe form factor with 16 GB GDDR6 memory sufficient for smaller inference or fine tuning jobs at 89.2 TFLOPS dense FP16.

Use Cases

LLM Training
MI250X

The MI250X supplies 383 TFLOPS dense FP16 and 128 GB memory that exceed the 89.2 TFLOPS dense FP16 and 16 GB memory of the Quadro RTX 5000.

LLM Inference
MI250X

Higher dense FP16 at 383 TFLOPS and 3277 GB/s bandwidth on the MI250X enable larger batch processing than the 89.2 TFLOPS and 448 GB/s on the Quadro RTX 5000.

Fine-tuning
MI250X

The MI250X provides 47.9 TFLOPS FP32 and 128 GB memory that support fine tuning at greater scale than the 11.2 TFLOPS FP32 and 16 GB on the Quadro RTX 5000.

Stable Diffusion
Quadro RTX 5000

The Quadro RTX 5000 at 230W TDP and PCIe form factor matches lighter diffusion workloads within its 89.2 TFLOPS dense FP16 limit.

Scientific Computing
MI250X

FP32 performance of 47.9 TFLOPS combined with 3277 GB/s bandwidth on the MI250X exceeds the 11.2 TFLOPS and 448 GB/s on the Quadro RTX 5000.

Frequently Asked Questions

What is the memory difference between MI250X and Quadro RTX 5000?▾

The MI250X contains 128 GB HBM2e while the Quadro RTX 5000 contains 16 GB GDDR6.

How does dense FP16 performance compare?▾

Dense FP16 reaches 383 TFLOPS on the MI250X and 89.2 TFLOPS on the Quadro RTX 5000.

What are the TDP values for each GPU?▾

The MI250X lists 560W TDP and the Quadro RTX 5000 lists 230W TDP.

Which GPU offers higher memory bandwidth?▾

The MI250X reaches 3277 GB/s while the Quadro RTX 5000 reaches 448 GB/s.

What interconnects are supported?▾

The MI250X supports Infinity Fabric and PCIe 4.0 while the Quadro RTX 5000 supports NVLink and PCIe 3.0.

How do the FP32 ratings differ?▾

FP32 performance measures 47.9 TFLOPS on the MI250X versus 11.2 TFLOPS on the Quadro RTX 5000.

Which is cheaper to rent, the MI250X or the Quadro RTX 5000?▾

Cloud rental prices for both the MI250X and Quadro RTX 5000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI250X have compared to the Quadro RTX 5000?▾

The MI250X has 128 GB of HBM2e memory. The Quadro RTX 5000 has 16 GB of GDDR6 memory.

Can I find MI250X and Quadro RTX 5000 GPUs available to rent right now?▾

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI250X and the Quadro RTX 5000?▾

The MI250X uses the CDNA 2 architecture (2021) while the Quadro RTX 5000 uses Turing (2018). The MI250X delivers 4.3x the dense FP16 throughput (383 vs 89.2 TFLOPS, both without sparsity) and 7.3x the memory bandwidth of the Quadro RTX 5000.

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How this page is made

  • Specifications come from the NVIDIA, AMD and Intel datasheets for the MI250X and the Quadro RTX 5000. Dense and sparse throughput are listed separately.
  • Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
  • The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
  • Read how we collect the data, or report an error on this page.

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