GPU comparison

MI300X vs Quadro RTX 4000

Specifications and current cloud pricing, side by side.

CDNA 3vsTuringUpdated 34 days ago

The MI300X wins for the most common use case of LLM inference because its 192 GB HBM3 VRAM and 1307.4 TFLOPS dense FP16 exceed the Quadro RTX 4000 specifications by wide margins derived from the listed numbers.

MI300X listed from $0.95/GPU/hrQuadro RTX 4000 listed from $0.56/GPU/hr

Right now, from live stock

  • Cheapest right now: Quadro RTX 4000 at $0.56/hr on Paperspace

    Deploy
  • Most providers in stock: Quadro RTX 4000 (1)

    See all offers

Specifications Compared

SpecMI300XQuadro RTX 4000
TDP750W125W
VRAM192 GB8 GB
CUDA CoresNot published2,304
FP8 (dense)2,614.9 TFLOPSNot published
Memory TypeHBM3GDDR6
ArchitectureCDNA 3Turing
FP16 (dense)1,307.4 TFLOPS57 TFLOPS
Form FactorsOAMPCIe
INT8 (dense)2,614.9 TOPSNot published
InterconnectInfinity Fabric, PCIe 5.0PCIe 3.0
Tensor CoresNot published288
FP32 Performance163.4 TFLOPS7.1 TFLOPS
FP64 Performance81.7 TFLOPSNot published
Memory Bandwidth5,300 GB/s416 GB/s
FP8 (with sparsity)5,229.8 TFLOPSNot published
FP16 (with sparsity)2,614.9 TFLOPSNot published
INT8 (with sparsity)5,229.8 TOPSNot published

Performance Analysis

The FP16 dense figure of 1307.4 TFLOPS on the MI300X exceeds the 57 TFLOPS dense FP16 on the Quadro RTX 4000 by a factor derived solely from those values. This ratio supports larger batch sizes during training and inference because the MI300X also supplies 5300 GB/s bandwidth compared to 416 GB/s. The FP32 value of 163.4 TFLOPS on the MI300X versus 7.1 TFLOPS on the Quadro RTX 4000 indicates that mixed precision paths using dense FP16 reduce computation time relative to pure FP32 paths on either GPU. Memory bandwidth of 5300 GB/s enables the MI300X to sustain higher throughput for sparse FP16 at 2614.9 TFLOPS while the Quadro RTX 4000 lacks published sparse figures. Dense FP8 at 2614.9 TFLOPS on the MI300X further widens the gap for quantized inference workloads against the Quadro RTX 4000.

Current On-Demand Offers

Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.

MI300X

MI300X is not offered on-demand by any provider we track right now. See the MI300X rental page for last-seen listed prices and a price alert.

Quadro RTX 4000

ProviderRegionGPUsPer GPU / hrInstance / hrDeploy
Paperspaceams11$0.56—Deploy

1 provider in stock, 5 offers (cheapest per provider shown). All Quadro RTX 4000 offers, price history and alerts

Which GPU to watchWatch the price of

Notify me when MI300X drops below a price

One email when the cheapest in-stock on-demand price per GPU-hour falls below your threshold.

QuantaCloud

Comparing providers? We broker across all of them.

Stop tab-switching between pricing pages. Tell us what you need, 16+ GPUs reserved or cluster capacity, and we return one quote at partner rates within 24 hours.

No waitlist24hr quote turnaroundInfiniBand fabric

Compare real-time pricing across 25+ providers

When to Choose the MI300X

The MI300X suits LLM training and inference tasks that require 192 GB HBM3 VRAM to hold models exceeding 8 GB capacity. Its 5300 GB/s bandwidth and dense FP16 at 1307.4 TFLOPS allow larger batch processing than the Quadro RTX 4000 can accommodate. Workloads needing Infinity Fabric interconnect and 2614.9 TFLOPS dense FP8 benefit from the MI300X at 750W TDP.

When to Choose the Quadro RTX 4000

The Quadro RTX 4000 fits scientific computing or fine tuning jobs constrained to 125W TDP and PCIe 3.0 slots. Its 8 GB GDDR6 VRAM and 7.1 TFLOPS FP32 handle smaller models where 416 GB/s bandwidth suffices without exceeding power limits of the MI300X.

Use Cases

LLM Training
MI300X

The MI300X supplies 192 GB HBM3 VRAM and 1307.4 TFLOPS dense FP16 to support large models beyond 8 GB capacity.

LLM Inference
MI300X

Dense FP16 at 1307.4 TFLOPS and 5300 GB/s bandwidth on the MI300X enable higher throughput than the Quadro RTX 4000 provides.

Fine-tuning
MI300X

The MI300X 2614.9 TFLOPS dense FP8 and 192 GB VRAM accommodate fine tuning of models that exceed Quadro RTX 4000 limits.

Stable Diffusion
Quadro RTX 4000

The Quadro RTX 4000 at 125W TDP and 7.1 TFLOPS FP32 meets requirements for smaller diffusion workloads without the 750W draw of the MI300X.

Scientific Computing
Quadro RTX 4000

The Quadro RTX 4000 delivers 7.1 TFLOPS FP32 at 125W TDP for compute tasks that fit within 8 GB GDDR6 VRAM.

Frequently Asked Questions

What is the memory bandwidth difference?▾

The MI300X reaches 5300 GB/s and the Quadro RTX 4000 reaches 416 GB/s.

Which GPU has higher dense FP16 performance?▾

The MI300X achieves 1307.4 TFLOPS dense FP16 compared to 57 TFLOPS dense FP16 on the Quadro RTX 4000.

What TDP values are listed for these GPUs?▾

The MI300X lists 750W TDP and the Quadro RTX 4000 lists 125W TDP.

What architectures do these GPUs use?▾

The MI300X uses CDNA 3 architecture and the Quadro RTX 4000 uses Turing architecture.

Which interconnect options appear in the specifications?▾

The MI300X includes Infinity Fabric and PCIe 5.0 while the Quadro RTX 4000 includes PCIe 3.0.

Which is cheaper to rent, the MI300X or the Quadro RTX 4000?▾

Cloud rental prices for both the MI300X and Quadro RTX 4000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI300X have compared to the Quadro RTX 4000?▾

The MI300X has 192 GB of HBM3 memory. The Quadro RTX 4000 has 8 GB of GDDR6 memory.

Can I find MI300X and Quadro RTX 4000 GPUs available to rent right now?▾

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI300X and the Quadro RTX 4000?▾

The MI300X uses the CDNA 3 architecture (2023) while the Quadro RTX 4000 uses Turing (2018). The MI300X delivers 22.9x the dense FP16 throughput (1,307.4 vs 57 TFLOPS, both without sparsity) and 12.7x the memory bandwidth of the Quadro RTX 4000.

Rent these GPUs

Each GPU page lists every current on-demand offer by provider, per GPU-hour, updated every minute.

Related comparisons

How this page is made

  • Specifications come from the NVIDIA, AMD and Intel datasheets for the MI300X and the Quadro RTX 4000. Dense and sparse throughput are listed separately.
  • Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
  • The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
  • Read how we collect the data, or report an error on this page.

Next steps