GPU comparison

MI250X vs RTX PRO 6000

Specifications and current cloud pricing, side by side.

CDNA 2vsBlackwellUpdated 31 days ago

The RTX PRO 6000 wins for the most common use case of LLM inference because its dense FP16 performance of 503.8 TFLOPS exceeds the MI250X dense FP16 performance of 383 TFLOPS while also offering sparsity modes and higher FP32 performance of 126 TFLOPS.

MI250X listed from $1.28/GPU/hrRTX PRO 6000 listed from $0.69/GPU/hr

Right now, from live stock

  • Cheapest right now: RTX PRO 6000 at $0.69/hr on RunPod

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  • Most providers in stock: RTX PRO 6000 (6)

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Specifications Compared

SpecMI250XRTX PRO 6000
TDP560W600W
VRAM128 GB96 GB
CUDA CoresNot published24,064
FP4 (dense)Not published2,015.2 TFLOPS
FP8 (dense)Not published1,007.6 TFLOPS
Memory TypeHBM2eGDDR7
ArchitectureCDNA 2Blackwell
FP16 (dense)383 TFLOPS503.8 TFLOPS
Form FactorsOAMPCIe
INT8 (dense)383 TOPS1,007.6 TOPS
InterconnectInfinity Fabric, PCIe 4.0PCIe 5.0
Tensor CoresNot published752
FP32 Performance47.9 TFLOPS126 TFLOPS
FP64 Performance47.9 TFLOPSNot published
Memory Bandwidth3,277 GB/s1,792 GB/s
FP4 (with sparsity)Not published4,030.4 TFLOPS
FP8 (with sparsity)Not published2,015.2 TFLOPS
FP16 (with sparsity)Not published1,007.6 TFLOPS
INT8 (with sparsity)Not published2,015.2 TOPS

Performance Analysis

The MI250X delivers FP16 dense performance of 383 TFLOPS against the RTX PRO 6000 FP16 dense performance of 503.8 TFLOPS while the RTX PRO 6000 also lists FP16 with sparsity at 1007.6 TFLOPS. The FP16 dense to FP32 ratio reaches 8 times on the MI250X based on 383 TFLOPS to 47.9 TFLOPS whereas the same dense ratio reaches 4 times on the RTX PRO 6000 based on 503.8 TFLOPS to 126 TFLOPS. Memory bandwidth of 3277 GB/s on the MI250X supports larger batch sizes than the 1792 GB/s bandwidth on the RTX PRO 6000 in memory intensive workloads.

Current On-Demand Offers

Cheapest secure on-demand offer per provider that is reported in stock right now, per GPU per hour; multi-GPU instances show the whole-instance price alongside. Deploy opens the DeployGPU console for providers on the platform, otherwise the provider's own site. Stock is rechecked every minute.

MI250X

MI250X is not offered on-demand by any provider we track right now. See the MI250X rental page for last-seen listed prices and a price alert.

RTX PRO 6000

ProviderRegionGPUsPer GPU / hrInstance / hrDeploy
RunPodglobal1$0.69—Deploy
Vast.aiCzechia, CZ1$1.47—Deploy
Massed Computeus-central-91$2.19—Deploy
VERDAFIN-HEL4$2.37$9.48Deploy
QuantaCloudus-midwest-41$2.39—Deploy

6 providers in stock, 20 offers (cheapest per provider shown). All RTX PRO 6000 offers, price history and alerts

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When to Choose the MI250X

The MI250X suits workloads that require 128 GB HBM2e memory and 3277 GB/s bandwidth at a TDP of 560W. Its OAM form factor and Infinity Fabric interconnect fit systems that prioritize dense FP16 performance of 383 TFLOPS over newer PCIe options.

When to Choose the RTX PRO 6000

The RTX PRO 6000 suits workloads that require FP32 performance of 126 TFLOPS and PCIe 5.0 interconnect in a PCIe form factor. Its dense FP16 performance of 503.8 TFLOPS and support for sparsity figures provide options in Blackwell architecture deployments at a TDP of 600W.

Use Cases

LLM Training
MI250X

The MI250X provides 128 GB HBM2e memory and 3277 GB/s bandwidth to handle larger models at FP16 dense performance of 383 TFLOPS.

LLM Inference
RTX PRO 6000

The RTX PRO 6000 delivers dense FP16 performance of 503.8 TFLOPS along with sparsity options and FP32 performance of 126 TFLOPS.

Fine-tuning
RTX PRO 6000

Stable Diffusion
RTX PRO 6000

The RTX PRO 6000 supplies FP8 dense performance of 1007.6 TFLOPS and memory bandwidth of 1792 GB/s in a PCIe configuration.

Scientific Computing
MI250X

The MI250X supplies FP32 performance of 47.9 TFLOPS with 128 GB HBM2e memory and 3277 GB/s bandwidth at 560W TDP.

Frequently Asked Questions

What is the memory difference between MI250X and RTX PRO 6000?▾

The MI250X contains 128 GB HBM2e memory while the RTX PRO 6000 contains 96 GB GDDR7 memory.

How does FP16 dense performance compare?▾

The MI250X reaches FP16 dense performance of 383 TFLOPS while the RTX PRO 6000 reaches FP16 dense performance of 503.8 TFLOPS.

What TDP values apply to each GPU?▾

The MI250X operates at a TDP of 560W and the RTX PRO 6000 operates at a TDP of 600W.

Which GPU has higher memory bandwidth?▾

The MI250X provides memory bandwidth of 3277 GB/s compared to 1792 GB/s on the RTX PRO 6000.

What FP32 performance do the GPUs deliver?▾

The MI250X delivers FP32 performance of 47.9 TFLOPS while the RTX PRO 6000 delivers FP32 performance of 126 TFLOPS.

Do the GPUs support the same interconnect?▾

The MI250X uses Infinity Fabric and PCIe 4.0 while the RTX PRO 6000 uses PCIe 5.0.

Which is cheaper to rent, the MI250X or the RTX PRO 6000?▾

Cloud rental prices for both the MI250X and RTX PRO 6000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI250X have compared to the RTX PRO 6000?▾

The MI250X has 128 GB of HBM2e memory. The RTX PRO 6000 has 96 GB of GDDR7 memory.

Can I find MI250X and RTX PRO 6000 GPUs available to rent right now?▾

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI250X and the RTX PRO 6000?▾

The MI250X uses the CDNA 2 architecture (2021) while the RTX PRO 6000 uses Blackwell (2025). The RTX PRO 6000 delivers 1.3x the dense FP16 throughput (503.8 vs 383 TFLOPS, both without sparsity) while the MI250X has 1.8x the memory bandwidth of the RTX PRO 6000.

Rent these GPUs

Each GPU page lists every current on-demand offer by provider, per GPU-hour, updated every minute.

Related comparisons

How this page is made

  • Specifications come from the NVIDIA, AMD and Intel datasheets for the MI250X and the RTX PRO 6000. Dense and sparse throughput are listed separately.
  • Prices and availability are live: every offer shown is an in-stock, on-demand listing from a provider we track, rechecked every minute.
  • The written comparison (overview, performance notes, when to choose each card, verdict, use cases and FAQ) was drafted with an AI model from the specification table above and passed an automated check that rejects any figure not in that table. It was last generated on . It contains no prices; those are always read live.
  • Read how we collect the data, or report an error on this page.

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